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Evidence-Based Answer Bupropion facilitates tobacco cessation reported at 6 months of follow-up compared with placebo or no pharmacological treatment (number needed to treat [NNT] with 150 to 300 mg of bupropion per day to yield one patient who stops smoking = 14
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During this process, the leaves are exposed to high levels of humidity and controlled heat, which results in a higher concentration of sugars and chemical compounds such as alkaloids and natural oils
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